CD 1
01. Cross Road Blues - Robert Johnson
02. That's All Right - Arthur 'Big Boy' Crudup
03. The Blues Had a Baby and They Named It Rock and Roll - Muddy Waters
04. Need Your Love So Bad - Fleetwood Mac
05. Lovin' In My Baby's Eyes - Taj Mahal
06. I'm Your Hoochie Coochie Man - Willie Dixon
07. Death Letter Blues - Son House
08. Whiskey Headed Blues (Remastered) - Sonny Boy Williamson
09. Muddy Water (A Mississippi Moan) - Bessie Smith And Her Band
10. Motherless Children - Blind Willie Johnson
11. Fort Worth and Dallas Blues - Leadbelly
12. Seminole Blues (Remastered) - Tampa Red
13. Johnny B. Goode (Live) - Johnny Winter
14. Got My Mojo Workin' - Otis Spann
15. River of No Return - The Jeff Healey Band

CD 2
16. Blues For Mama - Nina Simone
17. Pride and Joy - Double Trouble & Stevie Ray Vaughan
18. Killing Floor - The Electric Flag
19. I'd Rather Go Blind - Chicken Shack
20. Early in the Morning (Remastered) - Bill "Jazz" Gillum
21. Give Me an Old, Old Lady - Bukka White
22. Baby, Please Don't Go - Big Joe Williams
23. Stormy Monday Blues - Billy Eckstine & Earl Hines and His Orchestra
24. That Ain't Right - Mildred Bailey
25. Bumble Bee Blues - Memphis Jug Band
26. Worried Life Blues - Big Maceo Merriweather
27. Confessin' the Blues (with Jay McShann and His Band) - Jimmy Witherspoon
28. No More Women Blues - Lonnie Johnson
29. When the Sun Goes Down (Remastered) - Leroy Carr
30. Honky Tonk Train Blues - Meade Lux Lewis
31. Beer Drinkin' Woman (Remastered) - Memphis Slim

CD 3
32. Hard To Be - The Vaughan Brothers
33. Sawbuk - Top Topham
34. Cleanhead Blues - Eddie "Cleanhead" Vinson
35. Hold Me (Just a Little Longer Tonight) - Etta James
36. Baby Don't You Think I Know - Johnny Shines
37. Everyday I Have the Blues - Joe Williams
38. Broke and Hungry Blues - Big Maceo
39. Prowling Night Hawk - Robert Lee McCoy
40. Deep Down In the Ground (Remastered) - Sonny Boy Williamson
41. Rag Mama Rag - Blind Boy Fuller
42. I Love My Baby - Tommy McClennan
43. Mean Old Frisco Blues - Arthur "Big Boy" Crudup
44. Sweet Home Chicago - Robert Johnson
45. Friendless Blues - Big Bill Broonzy
46. She's Makin' a Fool Out of Me - Washboard Sam & His Washboard Band & Robert Brown
47. Billie's Blues (I Love My Man) - Billie Holiday and Her Orchestra

CD 4
48. Howling Wolf (Live) - Muddy Waters
49. I've Got To Forget You - Jellybread
50. Corinna - Taj Mahal
51. Let Me Miss You, Baby (Remastered) - Henry "Red" Allen
52. Back o' Town Blues - Louis Armstrong & His All Stars, Bob Haggart & Sidney Catlett
53. Rocks In My Bed (Remastered) - Duke Ellington & His Famous Orchestra & Ivie Anderson
54. Brand New Wagon - Count Basie and His Orchestra
55. St. Louis Blues - Jack Teagarden & His Big Eight & Joe Williams
56. The Blues in My Flat (Remastered) - Benny Goodman Quartet
57. Kassie Jones, Pt. 1 - Furry Lewis
58. Wipe It Off - Lonnie Johnson
59. Southern Can Is Mine - Blind Willie McTell
60. Key To the Highway 70 No. 1 - Brownie McGhee
61. Lend Me Your Love (Take 2) - Memphis Slim
62. Am I Wrong - Keb' Mo'
63. JB's Blues - Jeff Beck